Mekanisme Kejadian Dermatitis Kontak Iritan Akibat Paparan Buah Nanas (Ananas Comosus)

Irritant contact dermatitis is the skin's response to with various exposures substances such as biological, chemical and physical. The occurrence of DKI can be influenced by endogenous exogenous factors. Exogenous factors exposure from surrounding environment skin defense function presence a previous history atopic dermatitis. This literature review aims understand mechanism irritant due pineapple(Ananas comosus)especially in workers prevention. study was conducted collecting number books, research articles scientific journals that deal comosus). Literature has been Julì 2019. Pineapple or Ananas comosus member bromeliad family known cause stomatitis. extraction contains proteolytic enzymes bromelain, which are also physical irritants including citric acid calcium oxalate. Therefore, pineapple fruit one causes starts mild continuously causing barrier distrubsi activation cytokines T lymphocytes symptoms form inflammation lesions on